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18.06.09

Two awards for Dominik Paquet from the International Doctorate Program Protein Dynamics in Health and Disease

Member of the Elite Network of Bavaria Dominik Paquet is the winner of the Verum Award 2009 and the Leda Hanin Award for AD/PD 2009.   

Dominik Paquet, a PhD student in the doctorate program Protein Dynamics in Health and Disease in Munich, was awarded the 2nd prize for his presentation "A novel tau transgenic zebrafish model for drug discovery". The prize was awarded in recognition of outstanding scientific achievements within the EU-funded research project MEMOSAD. The prize winning research group developed a novel tau transgenic zebrafish model and investigated with this system the efficacy of two inhibitors of tau phosphorylation identified in a high-throughput screening process. While both inhibitors were highly active in cell cultures, only one of them displayed in vivo activity which is the prerequisite for its utilization as a therapeutic drug in Alzheimer disease. The new zebrafish transgenesis technology allows the modelling of numerous other human disorders which are based on misfolding or overexpression.

Dominik Paquet is also this year´s winner of the Leda Hanin Award, which is donated by the Cornelli Foundation in memory of Mrs Leda Hanin who made an invaluable contribution to the early AD/PD Conferences and is awarded to an outstanding researcher in the fields of Alzheimer’s or Parkinson’s Diseases.